West Side Story : Effect of low molecular weight procyanidins rich in extract from French maritime pine bark (OLIGOPIN®) on cardiovascular disease risk factors in stage-1 hypertensive subjects. Innovative randomized, double-blind, crossover, placebo-controlled intervention trial published in PHYTOmedicine.

OLIGOPIN® has been produced for over 40 years in the South of France by DRT Purextract®, a family owned company.

Proprietary Water- extraction process gives a highly purified pine bark extract, containing Monomers to Pentamers  and excluding non-bioavailable tanins. Factory is located at the heart of Les Landes of Gascony forest, raw material is sourced less than 10 km away from the production unit.

Diet supplementation for 5 weeks with OLIGOPIN® improves:

  • Systolic blood pressure of 6,36mmHg (14,75mmHg for women)
  • « Good » HDL cholesterol level by 14,06%
  • Apo B-100/Apo A-1 (corresponding to the LDL/HDL ratio) by 10,25%
  • Oxidized LDL level

As a comparison, 14% increase in good cholesterol is as twice as the effect of atorvastatin after 3 years therapy.

Join us on booth #GG125 and let’s discuss your Dietary supplements CVDs projects!

Yannick Piriou and Nathalie Luzecki-Michaud

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Phytomedicine is an international peer review journal, primarily therapy-oriented. Phytomedicine publishes innovative studies on efficacy, safety, quality and mechanisms of the action of specified plant extracts, phytopharmaceuticals and their isolated constituents. This includes clinical, pharmacological, pharmacokinetic, and toxicological studies of specified herbal medicinal products, herbal preparations and purified compounds, which have a defined and consistent quality, assuring reproducible pharmacological activity. The journal has a 5-year impact factor of 3.343.